目的 :比较安定与米索前列醇联合用药与单纯用米索在人工流产术中吸宫时镇痛效果。方法 :设A、B、C三组 ,A组于术前 2～ 3h阴道放置米索前列醇 4 0 0ug和术前 15～ 30min肌注安定 10mg ,B组单纯阴道置米索 ,C组不用任何药物。结果 :A组孕妇吸宫时疼痛明显轻于B组 (P <0 .0 1) ,A组无 1例发生人工流产综合症 ,术中出血亦较少。结论 :安定联合米索前列醇用于人工流产手术镇痛效果好 ,且简便、安全 ,能有效减轻孕妇人工流产时痛苦 ,预防人工流产综合症发生。 Objective: To compare the analgesic effect of diazepam and estradiol combined with misoprostol alone and misoprostol alone in abortion. Methods: A, B, C three groups, A group 2 to 3 hours before surgery vaginal misoprostol placed 40OOg and preoperative 15 ~ 30min intramuscular injection stability 10mg, B group simply vaginal misoprostol, C group without Any medicine. Results: The pain of the pregnant women in group A was significantly lower than that in group B (P <0.01). In group A, no one had abortion syndrome and bleeding was less. Conclusion: The combination of diazepam and misoprostol for analgesia induced by induced abortion is simple, safe and effective in relieving the pain of induced abortion in pregnant women and preventing the occurrence of abortion syndrome.