吸入一氧化氮作为近年来临床医学的一个重大进展 ,对其在临床的应用已进行了广泛的研究。作者综述了近年来国内外有关一氧化氮的代谢产物高铁血红蛋白 ,二氧化氮 ,近氧化亚硝酸根 ,亚硝基巯醇化合物等 )对机体的不良影响以及其毒性作用 ,致畸和致癌的可能性。并综述了有关对一氧化氮气体、一氧化氮吸入装置、以及与一氧化氮接触的人员所应采取的措施 Inhalation of nitric oxide as a major advance in clinical medicine in recent years, its clinical application has been extensively studied. The authors reviewed the adverse effects of methemoglobin, nitric oxide, nitrous oxide, nitroso-thiol compounds and other nitric oxide metabolites at home and abroad on the body as well as their toxic effects, teratogenicity and carcinogenesis possibility. And reviewed the steps to be taken with regard to nitric oxide gas, nitric oxide inhalation devices, and personnel in contact with nitric oxide