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目的探讨对直肠癌根治手术患者实施硬膜外麻醉联合全身麻醉的效果。方法选取2010年1月至2015年1月鞍山市肿瘤医院收治的108例直肠癌作为研究对象,按随机数字表法将其分为对照法和观察组,各54例。两组患者均行直肠癌根治术,对照组患者给予单纯全身麻醉,观察组患者行硬膜外麻醉复合全身麻醉,比较两组患者术前10 min(T0)、插管时(T1)、切除后(T2)、拔管时(T3)和拔管后10 min(T4)时的心率(HR)、血压及不良反应发生情况。结果 T1~T3时,观察组患者的HR值、血压值均明显低于对照组,差异均有统计学意义(均P<0.05);观察组患者的不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论对直肠癌根治手术患者实施硬膜外麻醉联合全身麻醉,效果更理想、安全。
Objective To investigate the effect of epidural anesthesia combined with general anesthesia in patients undergoing radical resection of rectal cancer. Methods A total of 108 patients with rectal cancer admitted to Anshan Cancer Hospital from January 2010 to January 2015 were selected as research objects. According to the random number table method, 54 cases were divided into control group and observation group. The patients in the control group were given general anesthesia. The patients in the observation group underwent epidural anesthesia combined with general anesthesia. The patients in the two groups were treated 10 min before operation (T0), at the time of intubation (T1), and resected (T2), extubation (T3) and 10 min after extubation (T4), heart rate (HR), blood pressure and adverse reactions. Results At T1 ~ T3, the HR and blood pressure of the observation group were significantly lower than those of the control group (all P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that of the control group There was statistical significance (P <0.05). Conclusion The implementation of epidural anesthesia combined with general anesthesia in radical resection of rectal cancer, the effect is more ideal and safe.