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目的:探讨早期乳酸清除率在重症社区获得性肺炎患者预后的评估价值。方法:收集本院2009年10月-2011年10月68例重症CAP患者,根据预后将患者分为存活组和死亡组,比较两组患者的6h乳酸清除率、PSI评分。以6h乳酸清除率10%为标准分为高乳酸清除率组和低乳酸清除率组,比较两组患者的病死率。结果:存活组的早期乳酸清除率明显高于死亡组(P<0.01),高乳酸清除率组的病死率明显低于低乳酸清除率组(P<0.01),PSI评分与血乳酸清除率呈显著负相关(r=-0.863,P<0.01)。结论:早期乳酸清除率联合PSI评分在评估重症CAP患者预后中具有较高的预测价值。
Objective: To evaluate the prognostic value of early lactic acid clearance in patients with severe community-acquired pneumonia. Methods: Sixty-eight patients with severe CAP in our hospital from October 2009 to October 2011 were collected. According to the prognosis, the patients were divided into survival group and death group. The lactic acid clearance and PSI score of 6h were compared between the two groups. 6h lactate clearance rate of 10% as a standard high-lactate clearance group and low lactate clearance group, the mortality of the two groups were compared. Results: The early lactic acid clearance rate in survival group was significantly higher than that in death group (P <0.01). The mortality in high lactic acid clearance group was significantly lower than that in low lactic acid clearance group (P <0.01). PSI score and blood lactic acid clearance rate Significant negative correlation (r = -0.863, P <0.01). Conclusion: Early lactic acid clearance combined with PSI score has a high predictive value in assessing the prognosis of critically ill patients with CAP.