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目的:通过比较在急性缺血性脑卒中胰岛素抵抗(IR)患者与非IR组中超敏C反应蛋白(hsCRP)的变化情况,进行相关的统计学分析,探讨其早期水平的变化是否会对急性脑卒中患者的病情预后产生影响。方法:建立研究人群的组别,描述研究人群的分布特征,设立参照及实验标准,进行各项研究指标的检测,以及患者完整的随访观察,收集相关全面,详细的临床研究资料,筛选有效及合格的信息,及时输入研究样本的资料。结果:根据研究统计分析,我们可以看出在血清中hsCRP的水平,并不随卒中后的时间推移有显著改变。具有危险因素的受试者,较阴性对照组,有更高的hsCRP水平。结论:我们发现hsCRP在急性缺血组IR中有较高表达,与患者不良终点事件的预后,有一定的线性相关性。
OBJECTIVE: To compare the changes of hsCRP in patients with acute ischemic stroke with insulin resistance (IR) and those in non-IR group, and to investigate whether changes in their early stage would affect the acute Stroke patients have an impact on the prognosis. Methods: To establish a group of study population, to describe the distribution characteristics of the study population, to set up reference and experimental standards, to carry out the detection of various research indicators and patients’ complete follow-up observation, to collect relevant comprehensive and detailed clinical research data, to screen effective and Qualified information, timely input sample data. Results: Based on the research statistical analysis, we can see that the level of hsCRP in serum does not change significantly with the passage of time after stroke. Subjects with risk factors had higher hsCRP levels than the negative controls. CONCLUSIONS: We found that hsCRP is highly expressed in the IR of acute ischemic group and has a certain linear correlation with the prognosis of patients with poor endpoint.