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选取我院2015年1月~2016年2月期间收治的70例老年T_2DM患者为,随机将其分为对照组35例。给予甘精胰岛素治疗,观察组35例在加以磷酸西格列汀治疗。结果观察组HOMA-IR、HOMA-β及空腹C肽水平优于对照组,(P<0.05);治疗后两组HbA_(1c)、FBG及2h PG水平均显著下降,观察组优于对照组(P<0.05);不良反应发生率低于对照组,(P<0.05)。结论老年T2DM患者给予磷酸西格列汀联合甘精胰岛素治疗可有效改善胰岛功能,控制血糖水平。
A total of 70 elderly patients with T2DM treated in our hospital from January 2015 to February 2016 were randomly divided into control group (35 cases). Given insulin glargine treatment group 35 cases were treated with sitagliptin phosphate. Results The levels of HOMA-IR, HOMA-β and fasting C-peptide in the observation group were better than those in the control group (P <0.05). The levels of HbA 1c, FBG and 2h PG in both groups were significantly decreased after treatment (P <0.05). The incidence of adverse reactions was lower than that of the control group (P <0.05). Conclusion The treatment of elderly patients with T2DM with sitagliptin phosphate and insulin glargine can effectively improve islet function and control blood sugar level.