论文部分内容阅读
非酒精性脂肪肝与胰岛素抵抗和遗传易感性密切相关。它被认为是代谢综合征在肝脏的表现。精神分裂症病人发生非酒精性脂肪肝的比率高于普通人群。本文作者通过归纳和分析整理,发现精神分裂症病人社会功能退缩,运动减少,有物质滥用,吸烟等不良生活方式;抗精神病药物所致内分泌紊乱和嗜睡,产生肥胖;同时糖代谢和胰岛素分泌异常,伴发2型糖尿病等因素是导致非酒精性脂肪肝发生的原因。针对发病机制的临床治疗包括改善不良生活方式、减肥、降糖等。
Non-alcoholic fatty liver disease is closely related to insulin resistance and genetic predisposition. It is thought to be a manifestation of the metabolic syndrome in the liver. The rate of nonalcoholic fatty liver disease in schizophrenic patients is higher than in the general population. Through summarizing and analyzing, the author found that schizophrenic patients have social functions such as withdrawal, exercise reduction, substance abuse, smoking and other unhealthy lifestyles; endocrine disorders and drowsiness caused by antipsychotic drugs and obesity; meanwhile, glucose metabolism and abnormal insulin secretion , Associated with type 2 diabetes and other factors is the cause of non-alcoholic fatty liver. Clinical treatment for the pathogenesis includes improving poor lifestyles, weight loss, hypoglycemic and so on.