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目的 :探讨宫颈解脲支原体 (UU)在不同状态下与不良妊娠结局的关系。方法 :通过聚合酶链反应 (PCR)对 2 10例孕妇的宫颈分泌物进行uuDNA检测 ,用酶联免疫吸附试验 (ELISA)检测孕妇血清抗uuIgM ,,以两项检测结果同时阳性做为宫颈uu感染的标准 ,以uuDNA阳性而血清抗uuIgM阴性做为宫颈uu的携带状态的标准。结果 :2 10例孕妇中宫颈分泌物uuDNA阳性 10 0例 ,占 47.6 % ,宫颈分泌物uuDNA及血清抗uuIgM均为阳性者 6 2例 ,占分娩总数的 2 9.5 % ,占宫颈分泌物阳性者的 6 2 % ;感染组分别与携带组和阴性对照组比较 ,胎膜早破、早产、剖宫产、新生儿窒息、低体重儿、新生儿肺炎、绒毛膜羊膜炎等不良妊娠结局的发生率明显升高 ,差异显著 (P <0 .0 5 ) ,而携带组与阴性对照组相比 ,无显著差异 (P >0 .0 5 )。结论 :宫颈uu发生感染与不良妊娠结局的发生密切相关 ;正常携带状态与其无相关性 ;宫颈uu感染导致不良妊娠结局是通过宫腔内感染引起绒毛膜羊膜炎实现的
Objective: To investigate the relationship between cervical Ureaplasma urealyticum (UU) and adverse pregnancy outcomes under different conditions. Methods: UuDNA was detected in cervical secretions of 210 pregnant women by polymerase chain reaction (PCR), serum anti-uuIgM was detected by enzyme-linked immunosorbent assay (ELISA), and the results of two tests were positive as cervical uu The standard of infection, with uuDNA positive and serum anti-uuIgM negative as cervical uu carrying status of the standard. Results: Totally 62 cases of uuDNA positive cervical secretions were found in 2 10 pregnant women, accounting for 47.6% of the total, while uuDNA of cervical secretions and serum anti-uuIgM were positive, accounting for 2 9.5% of the total number of deliveries, accounting for positive cervical secretions Compared with the control group and the carrying group and the negative control group. The incidence of adverse pregnancy outcomes such as premature rupture of membranes, premature delivery, cesarean section, neonatal asphyxia, low birth weight infants, neonatal pneumonia, chorioamnionitis and so on (P <0.05), while there was no significant difference between the carrying group and the negative control group (P> 0.05). Conclusion: The infection of cervical uu is closely related to the occurrence of adverse pregnancy outcome; the normal state of carriage is not related to it; the uu infection caused by cervical uu is the result of chorioamnionitis caused by intrauterine infection