Tuner syndrome是最常见的染色体异常疾病之一。约1/3 000育龄妇女发病。作者对22例有家族遗传史的患者作了体格检查、纯音测听及鼓室压力检查。其中8例作了CT扫描。82%患者有慢性或复发性耳部感染史,11例(50%)曾行鼓膜切开和置管术,4例(16%)曾行鼓室成形术或鼓室乳突手术。术中发现有听小骨破坏并有胆脂瘤形成(10%)。10例(45%)有明显的中耳渗出征。16例(73%)至少 Tuner syndrome is one of the most common chromosomal abnormalities. About 1/3000 of women of childbearing age. The authors performed physical examination, pure tone audiometry and tympanic pressure on 22 patients with a family history of disease. Eight of them had CT scan. 82% of patients had a history of chronic or recurrent otitis media, 11 cases (50%) underwent tympanotomy and catheterization, and 4 (16%) underwent tympanoplasty or tympanotomy. Osteotomy was found during operation (10%). Ten cases (45%) had significant signs of middle ear exudation. 16 cases (73%) at least