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目的观察乙型肝炎病毒感染的孕妇孕中晚期肝功能的变化。方法初次孕检的早孕孕妇乙肝表面抗原阳性但肝功能正常者52例为观察组,于孕32周化验肝功能,同时抽取健康孕妇也共52例为对照组。结果观察组出现4例肝功能异常,对照组出现3例肝功能异常。两组比较,差异无统计学意义(P>0.05)。结论乙肝病毒感染的孕妇只要肝功能正常,可以安全度过孕期。
Objective To observe the changes of liver function in pregnant women with hepatitis B virus infection during the second trimester of pregnancy. Methods Fifty-two pregnant women with positive hepatitis B surface antigen (HBsAg) but normal liver function in the first trimester of pregnancy were enrolled in the study. Liver function was tested at 32 weeks’ gestation, and a total of 52 healthy pregnant women were also selected as the control group. Results In the observation group, 4 cases of liver dysfunction occurred, and 3 cases of liver dysfunction in the control group. There was no significant difference between the two groups (P> 0.05). Conclusion Pregnant women with hepatitis B virus infection can pass the pregnancy safely as long as their liver function is normal.