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目的:探讨小剂量胺碘酮联合美托洛尔方案治疗扩张型心肌病伴恶性室性心律失常的疗效。方法:选取我院在2013年1月-2015年1月期间收治的76例扩张型心肌病伴恶性室性心律失常患者,按照盲选法将患者分成对照组(38例,采用美托洛尔治疗)和观察组(38例,采用小剂量胺碘酮联合美托洛尔治疗),随访1年,观察两组治疗效果。结果:观察组患者治疗的效果、动态心电图改善的情况以及LVEF和LVED改善的情况都明显优于对照组(P<0.05)。另外,两组患者均未发生严重的不良反应。结论:采用小剂量胺碘酮+美托洛尔方案治疗扩张型心肌病伴恶性室性心律失常效果显著,值得临床推广。
Objective: To investigate the efficacy of low-dose amiodarone combined with metoprolol in the treatment of dilated cardiomyopathy with malignant ventricular arrhythmia. Methods: A total of 76 patients with dilated cardiomyopathy and malignant ventricular arrhythmias admitted to our hospital from January 2013 to January 2015 were selected and divided into control group (blind control group, 38 cases, metoprolol Treatment) and observation group (38 cases, with low-dose amiodarone combined with metoprolol treatment), followed up for 1 year, the two groups were treated. Results: The effect of treatment, the improvement of ambulatory electrocardiogram and the improvement of LVEF and LVED in observation group were significantly better than those in control group (P <0.05). In addition, no serious adverse reactions occurred in both groups. Conclusion: A small dose of amiodarone + metoprolol in the treatment of dilated cardiomyopathy with malignant ventricular arrhythmia effect is worthy of clinical promotion.