佝偻病是目前危害婴幼儿健康发育的常见病之一。为了寻求佝偻病发病原因及对机体免疫功能的影响,我们对48例小儿佝偻病的体液免疫进行了观察。48例佝偻病患儿系我院和成都市儿童医院确诊病儿,共分5组;其中0～6月组10例;7～12月组5例;13～18月组9例;19～24月组5例;25～36月组19例,分别与同年龄正常儿对照(见附表),5个年龄组免疫球蛋白均有不同程度的改变,IgG、IgA 普遍降低,而IgM 普遍升 Rickets is one of the common diseases that endanger the healthy development of infants and young children. In order to find out the causes of rickets and its impact on immune function, we observed the humoral immunity of 48 children with rickets. 48 cases of rickets in our hospital and Chengdu Children’s Hospital diagnosed sick children, divided into 5 groups; of which 0 to 6 months in 10 cases; 7 to December group 5 cases; 13 to 18 months in 9 cases; 19 to 24 5 cases in the month group; 19 cases in the 25-36 month group, which were respectively compared with the normal children of the same age (see the attached table). The immunoglobulin in 5 age groups all changed to different degrees, with generally decreased IgG and IgA,