Does hemispheric lateralization inlfuence therapeutic effects of transcranial direct current stimula

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This study investigated the effect of transcranial direct current stimulation (tDCS) polarity depending on lat-eralized function of task property in normal individuals performing visuomotor and simple repetitive tasks. Thirty healthy participants with no neurological disorders were recruited to participate in this study. Partici-pants were randomly allocated into active or control condition. For the active condition, tDCS intensity was 2 mA with stimulation applied for 15 minutes to the right hemisphere (tDCS condition). For the sham control, electrodes were placed in the same position, but the stimulator was ted off after 30 seconds (sham con-dition). The tapping and tracking task tests were performed before and after for both conditions. Univariate analysis revealed signiifcant difference only in the tracking task. For direct comparison of both tasks within each group, the tracking task had signiifcantly higher Z score than the tapping task in the tDCS group (P < 0.05). Thus, our study indicates that stimulation of the right hemisphere using tDCS can effectively improve visuomotor (tracking) task over simple repetitive (tapping) task.
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