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中枢神经系统感染的致死率高达8-13%.根据感染症状以及脑膜刺激征或颅内高压或神经损害体征等临床上可疑诊为脑膜脑炎,而病原学诊断则依赖于脑脊液(CSF)病原微生物的鉴定.CSF细胞化学变化的研究对大多数病人做出了诊断;然而在4-13%的细菌性脑膜脑炎的病例中其CSF的变化无特异性,与无菌性脑膜脑炎难以区别.病因学诊断依赖于CSF病原菌的分离,这种方法对细菌性脑膜脑炎需48-72小时,而对病毒性脑膜脑炎则需2周.这种方法有20-40%的细菌性脑
The mortality of CNS infections is as high as 8-13% .The diagnosis of meningoencephalitis is clinically suspicious based on the symptoms of infection and signs of meningeal irritation or signs of intracranial hypertension or nerve damage, whereas etiological diagnosis depends on CSF pathogens Identification of microorganisms The study of CSF cytochemical changes has led to the diagnosis of most patients; however, CSF changes are nonspecific in 4-13% of cases of bacterial meningoencephalitis and are difficult to treat with aseptic meningoencephalitis The etiological diagnosis depended on the isolation of CSF pathogens, which required 48-72 hours for bacterial meningoencephalitis and 2 weeks for viral meningoencephalitis, with 20-40% bacterial brain