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The C2 hydrotreating catalyst (PEC-21) developed independently by the PetroChina Petrochemical Research Institute (PRI) has been operating continuously for one month in the first stage of reactor in the 460 kt/a ethylene unit at the PetroChina Lanzhou Petrochemical Branch Company, indicating that this catalyst has been successfully applied in commercial scale. The uninterrupted supervision data have shown that the PEC-21 catalyst worked smoothly and the temperature distribution in the reactor bed was satisfactory, while delivering product with acetylene content meeting the spec, denoting that this catalyst has an excellent overall performance.