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目的了解2016年医院门诊药房抗高血压药的用药情况,为临床应用提供参考,促进临床合理应用。方法随机抽取医院2016年门诊药房的高血压处方1 000张,统计患者性别、年龄、费别,结合各个药物的限定日剂量(DDD)值、处方总用量、销售金额计算用药频度(DDDS)、限定日费用(DDC)、药物利用指数(DUI),分析联合用药情况。结果男性患者>女性患者,医保患者>自费患者;按DDDS排序:血管紧张素Ⅱ受体阻断剂(ARB)>钙通道阻滞剂(CCB)>利尿药>复方制剂>血管紧张素转化酶抑制剂(ACEI)>β-阻滞剂;DDC排序:缬沙坦胶囊>硝苯地平控释片>厄贝沙坦;DUI全部≤1,联合用药最常见组合CCB+ARB、ARB+噻嗪类利尿药。结论医院临床用药基本合理。
Objective To understand the use of antihypertensive drugs in hospital outpatient pharmacies in 2016, and to provide reference for clinical application and to promote the rational clinical application. Methods A total of 1 000 hypertension prescriptions were collected from outpatient clinics in 2016. The patients’ sex, age and fee were calculated. DDD, DDDS, DDDS, , DDC, and DUI, to analyze the combination of drugs. Results Male patients> Female patients, Medicaid patients> At-risk patients; Sorted by DDDS: Angiotensin II Receptor Blocker (ARB)> Calcium Channel Blocker (CCB)> Diuretic> Compound> Angiotensin Converting Enzyme DDT: Valsartan capsules> nifedipine GITS> irbesartan; DUI all ≤1, the combination of the most commonly used combination CCB + ARB, ARB + thiazide Diuretic. Conclusion The hospital clinical medication is reasonable.