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为研究血管紧张素转换酶抑制剂蒙诺和 HMG-Co A还原酶抑制剂普拉固对糖尿病大鼠心脏保护作用 ,用蒙诺 (15 mg.kg- 1 /d)和普拉固 (2 0 mg.kg- 1 /d)对糖尿病大鼠进行五周治疗 ,观察两药对糖尿病大鼠心肌结构的保护作用。结果显示 ,应用蒙诺和普拉固可延缓实验性糖尿病大鼠心肌结构的病理学进展。
To investigate the cardioprotective effect of angiotensin converting enzyme inhibitor Monopril and HMG-Co A reductase inhibitor prasugrel on diabetic rats, Mono (15 mg.kg-1 / d) and prasugrel 0 mg.kg-1 / d) for five weeks in diabetic rats to observe the protective effect of the two drugs on myocardial structure in diabetic rats. The results show that the use of Monopril and Prasugo can delay the pathological progression of myocardial structure in experimental diabetic rats.