鼻硬结病是鼻与呼吸道的一种慢性传染性肉芽肿性疾病。Toppozoda等(1983)总结欧洲、亚洲、非洲及中美洲的25个国家,都有地方性的鼻硬结病发病区。从查到的国外文献资料来看,全世界的病例已达万例以上,实际发病数还要多。中国的鼻硬结病截止到1983年,全部病例已近2000例。目前,鼻硬结病的临床诊断、组织病理学及细菌学这三方面尚存在一些问题。临床诊断方面是鼻硬结病的早期萎缩期与臭鼻症的鉴别诊断问题。临床医生在非流行病区发现早期萎缩期的鼻硬结病例,往往不容易识别。在组织病理学 Rhinosinusitis is a chronic, contagious granulomatous disease of the nose and respiratory tract. Toppozoda et al. (1983) concluded that in 25 countries in Europe, Asia, Africa and Central America, there are endemic areas with a history of epistaxis. From the foreign literature found, the number of cases in the world has reached more than 10,000 cases, the actual incidence even more. China’s nose and nose disease ended in 1983, nearly 2000 cases of all cases. At present, there are still some problems in clinical diagnosis, histopathology and bacteriology of rhinosclerosis. Clinical diagnosis is the early diagnosis of nasal degeneration and blemished nose syndrome differential diagnosis. Clinicians have found cases of nasal ascites in the early stages of atrophy in non-endemic areas and are often not easily identified. In histopathology