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目的探讨高血压患者踝臂脉搏波速度(baPWV)与心血管疾病危险因素之间的关系。方法以2011年来我院健康体检的941人为研究对象,全部受检者控制饮食后在清晨空腹安静状态下采静脉血检测UA、血糖(Glu)、血脂,电子血压计测量血压,同时采集既往血压、血糖、血脂、血尿酸病史;采用身高体重电子测量仪测量身高、体重,计算BMI;通过肢体动脉检测仪获得踝臂脉搏波速度(baPWV),对该人群的性别、年龄、身高、体重、踝臂脉搏波速度(baPWV)、血压、血糖、血脂、血尿酸、BMI等检查结果进行统计分析。结果高血压组年龄、BMI、舒张压、收缩压、空腹血糖、胆固醇、甘油三酯、LDL、血尿酸水平均高于正常血压组,而HDL却低于正常血压组,两组之间差异有统计学意义(P<0.05)。高血压组的baPWV均值明显高于正常血压组,差异有统计学意义(P<0.05)。高血压患者男性组与女性组比较收缩压存在显著性差异(P<0.05),但年龄、舒张压无明显差异(P>0.05)。男性组baPWV值虽稍高于女性组,但无统计学意义(P>0.05)。不同级别的高血压患者的年龄比较无统计学差异(P>0.05)。不同级别的高血压患者收缩压、舒张压和baPWV值存在显著差异(P<0.05)。结论高血压患者与正常血压组在各项心血管危险因素之间均存在显著差异。高血压患者的baPWV值较正常血压组明显增高,PWV可作为高血压患者动脉硬化改变的检测指标之一。不同级别的高血压患者baPWV值存在显著差异(P<0.05),血压水平越高,对动脉弹性影响越大。
Objective To investigate the relationship between ankle brachial-pulse wave velocity (baPWV) and cardiovascular risk factors in hypertensive patients. Methods A total of 941 healthy people in our hospital from 2011 to 2011 were enrolled in this study. All subjects underwent fasting fasting morning UA, Glu, lipids, blood pressure, , Blood glucose, blood lipids and blood uric acid. The height and weight were measured by height and weight electronic meter, and the BMI was calculated. The ankle-brachial pulse wave velocity (baPWV) was obtained by limb arterial detector. The gender, age, height, Ankle brachial pulse wave velocity (baPWV), blood pressure, blood glucose, blood lipids, serum uric acid, BMI and other test results for statistical analysis. Results The age, BMI, diastolic blood pressure, systolic blood pressure, fasting blood glucose, cholesterol, triglyceride, LDL and serum uric acid in hypertensive group were higher than those in normal blood pressure group, but HDL was lower than that in normal blood pressure group Statistical significance (P <0.05). The mean value of baPWV in hypertension group was significantly higher than that in normal blood pressure group, the difference was statistically significant (P <0.05). There was significant difference in systolic blood pressure between male patients and hypertensive patients (P <0.05), but there was no significant difference in age and diastolic pressure (P> 0.05). Although the value of baPWV in male group was slightly higher than that in female group, it was not statistically significant (P> 0.05). There was no significant difference in the age of patients with different grades of hypertension (P> 0.05). Systolic blood pressure, diastolic blood pressure and baPWV were significantly different among different levels of hypertension (P <0.05). Conclusion There are significant differences among cardiovascular risk factors in hypertensive patients and normal blood pressure patients. The value of baPWV in hypertensive patients was significantly higher than that in normal blood pressure group, and PWV could be used as one of the detection indexes of arteriosclerosis in hypertensive patients. The baPWV values of different levels of hypertension patients were significantly different (P <0.05), the higher the blood pressure level, the greater the impact on arterial elasticity.