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目的分析郑州大学第三附属医院药品不良反应的发生情况及其给患者带来的危害,以促进临床合理用药。方法对郑州大学第三附属医院2009年6月—2009年12月收集到的57例药品不良反应报告进行回顾性分析。结果 57例药品不良反应中60岁以上19例(33.33%),合并用药39例(68.42%),单独用药18例(31.58%)。给药途径以静脉用药为主,占87.72%;所涉及的药物共有24个品种,由抗菌药物导致的ADR所占比例61.40%;ADR常见表现为皮肤及附件的损害,其次为全身性损害和消化系统反应。结论 ADR发生因素较多,应加强和重视ADR的报告和监测工作,提高临床安全用药水平。
Objective To analyze the incidence of adverse drug reactions and its harm to patients in the Third Affiliated Hospital of Zhengzhou University in order to promote rational clinical use. Methods A retrospective analysis of 57 adverse drug reactions reports collected from June 2009 to December 2009 in the Third Affiliated Hospital of Zhengzhou University was conducted. Results Among the 57 cases, there were 19 cases (33.33%) over 60 years old in the adverse drug reactions, 39 cases (68.42%) were combined and 18 cases (31.58%) were used alone. The main route of administration was intravenous drug, accounting for 87.72%; the drug involved a total of 24 varieties, accounting for 61.40% of ADR caused by antimicrobial drugs; ADR common manifestations of skin and attachment damage, followed by systemic damage and Digestive system reaction. Conclusion There are many factors that cause ADR. The report and monitoring of ADR should be strengthened and valued, and the level of clinical safety medication should be improved.