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目的 探讨食管癌锁骨上淋巴结转移放射治疗的价值及影响预后因素。方法 1984 年9 月至1992 年12 月收治食管癌锁骨上淋巴结转移111 例,均采用60Co 外照射,食管DT60 ~70Gy,锁骨上DT50~66Gy。结果 治疗后的1、3 、5 年生存率分别为49.6 % 、10.8% 、6.3 % ;病变长度≤5.0 cm 、5.1 ~8 cm 、> 8 cm 的5 年生存率分别为15% 、2.5 % 、0( P<0.05) ;疗终X线表现基本消失与部分消失的5 年生存率分别为12.5% 、1.8%( P< 0.05);锁骨上淋巴结<3 cm 和≥3 cm 的5 年生存率分别为8.1 % 、0 。结论 食管癌锁骨上淋巴结转移应积极治疗,淋巴结大小、食管病灶长度、疗终X线表现、放疗剂量是影响预后的主要因素
Objective To investigate the value of radiotherapy for the treatment of esophageal cancer with supraclavicular lymph node metastasis and its prognostic factors. Methods From September 1984 to December 1992,111 cases of esophageal cancer with supraclavicular lymph node metastases were treated with 60Co external irradiation, esophageal DT60 ~70Gy, and supraclavicular DT50 ~ 66Gy. Results The 1-, 3-, and 5-year survival rates after treatment were 49.6 %, 10.8%, and 6.3 %, respectively; the 5-year lesion lengths were ≤ 5.0 cm, 5.1 to 8 cm, and > 8 cm. The survival rates were 15%, 2.5%, and 0, respectively (P<0.05). The 5-year survival rates at the end of treatment and partial disappearance of the X-ray findings were 12.5% and 1.8%, respectively (P< The 5-year survival rate of <3 cm and ≥3 cm in supraclavicular lymph nodes was 8.1% and 0, respectively. Conclusion The treatment of esophageal cancer with supraclavicular lymph node metastasis should be actively treated. The size of lymph nodes, the length of esophageal lesions, the end-of-treatment X-ray findings, and the dose of radiotherapy are the main factors affecting the prognosis.