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腹膜有自然的纤溶作用,因而纤维性粘连可以被吸收.但在开腹于术后,腹膜的纤溶活力明显减小,而在腹膜炎时甚至可完全消失,从而使纤维素持续存在.近数年来,对纤维素在腹膜炎发病机理中的重要性有所争论.纤维素渗出在伤口闭合和愈合过程中很重要,而且为腹腔感染的局限和脓肿形成所必须.在抗菌素应用以前时代,上述作用是腹膜炎病人得以生存的唯一途径.虽纤维素的有益作用显而易见,但也有关于纤维素的形成产生不利影响的报道:由于纤维素捕捉细菌,从而防止了全身脓毒病,但它也会起到保护细菌,使之免受机体防御机制的影响而有助干脓肿形成.在实验中已有肝素治疗腹膜炎提高动物生存率的报道.本研究旨在估计纤维素捕捉作用对大肠杆菌致病性和全身抗菌素治疗的影响.
Peritoneal fibrinolytic effect, and thus fibrous adhesions can be absorbed.But in the open surgery, the peritoneal fibrinolytic activity decreased significantly, but in peritonitis or even disappear completely, so that cellulose persists. Over the years, the importance of cellulose in the pathogenesis of peritonitis has been debated.Cellulose oozing is very important in wound closure and healing process, and is necessary for the limitation of abdominal infection and abscess formation.In the previous era of antibiotic application, This is the only way in which patients with peritonitis can survive Although the beneficial effects of cellulose are evident, there are also reports of adverse effects on the formation of cellulose: Since cellulose captures bacteria and thus prevents systemic sepsis, it also Play a role in protecting bacteria from the body’s defensive mechanisms and helping dry abscess formation.Heart has been reported in the trial of heparin treatment of peritonitis to improve animal survival.This study aimed to estimate the effect of cellulose capture on E. coli The impact of sexual and systemic antibiotic therapy.