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百喘朋是治疗哮喘的常用药,由麻黄碱和苯海拉明各25mg组成,系小型糖衣片。保管不慎易被小儿误当糖丸吞服,造成中毒。据文献记载:麻黄碱的成人致死量为600mg,苯海拉明的致死量为40mg/Kg。笔者于1986年收治2例百喘朋中毒,现报告如下。例1,男,4岁。误服百喘朋20片,4小时后被送进医院,检查体温37℃,皮肤潮红,躁动不安,谵妄,肌肉震颤,阵发性惊厥,无脑膜刺激征,双瞳扩大,对光反应迟钝,心率140次/次,呼吸急促,腹软。即给以1:5000高锰酸钾溶液冼胃,硫酸镁导泻;静滴10%葡萄糖液,肌注速尿15mg,冬眠灵10mg,12小时后,中毒症状消失。
Baichuan Peng is a commonly used medicine for the treatment of asthma, composed of ephedrine and diphenhydramine 25mg, Department of small sugar-coated tablets. Accidentally easy to be mistaken for children pills swallowed, resulting in poisoning. According to the literature, the lethal dose of ephedrine to adults is 600 mg, and the lethal dose of diphenhydramine to 40 mg / kg. The author admitted in 1986, two cases of Bai Peng Peng poisoning, are as follows. Example 1, male, 4 years old. Obese Bai Bai Peng 20, 4 hours after being taken to the hospital, check the body temperature 37 ℃, the skin flushing, restlessness, delirium, muscle tremors, paroxysmal convulsions, meningeal irritation, double pupil dilation, dull to light , Heart rate 140 times / time, shortness of breath, abdominal softness. Give 1: 5000 potassium permanganate solution stomach, magnesium sulfate catharsis; intravenous infusion of 10% glucose solution, intramuscular furosemide 15mg, winter sleep spirit 10mg, 12 hours later, the symptoms of poisoning disappeared.