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[目的]通过比较某纺织厂噪声接触人员与健康人群动脉顺应性的差异,观察其噪声接触人员动脉顺应性的变化,为进一步制定相应的预防与控制措施提供科学依据。[方法]对噪声作业点用HS6288系列噪声分析仪监测作业场所噪声强度,并进行频谱分析,计算累积噪声暴露量(CNE);使用动脉脉搏波形分析仪测量550名某纺织厂女性噪声接触人员(观察组)的动脉功能(大动脉弹性指数C_1、小动脉弹性指数C_2)、收缩压(Sbp)、舒张压(Dbp)、脉压(Pp)、平均动脉压(Map),另取96名同单位不接触职业性有害因素女性工作人员作为对照组。[结果](1)作业环境噪声强度为80.1～113.5dB(A),总的点超标率为92.5%。(2)观察组中检出高血压50人,检出率为9.1%;动脉顺应性异常检出244人,检出率为44.4%,其中以单纯C_2降低为主,占整个动脉顺应性异常的75.0%。(3)观察组的Sbp、Map和Pp显著高于对照组(P﹤0.05),C_1、C_2明显低于对照组(P﹤0.05)。(4)观察组噪声暴露强度在100dB以上的车间,其噪声接触人员的Sbp、Map、Pp均显著高于噪声﹤100dB的车间和对照组(P﹤0.05),C_2显著低于对照组(P﹤0.05)。(5)观察组中Sbp、Dbp、Map和Pp均与C1存在负相关关系(P﹤0.01),C_2与年龄、Sbp、Dbp、Map、Pp存在负相关关系(P﹤0.01)。(6)分别以观察组的C_1和C_2为因变量,以年龄(Age)、累积噪声暴露量(CNE)、Sbp、Dbp和Map为自变量进行多元回归分析,从方程中可以看出Sbp是影响C_1、C_2的主要因素,其次是Dbp,CNE对C_1有一定的影响。[结论]该纺织厂噪声接触人员的大、小动脉顺应性均降低,说明长时间接触噪声能导致血管功能受影响,动脉弹性下降。
[Objective] The purpose of this study was to compare the changes of arterial compliance between noise-exposed workers and healthy people in a textile mill and observe the changes of arterial compliance of noise-exposed workers so as to provide a scientific basis for further development of appropriate prevention and control measures. [Methods] The noise intensity at work site was monitored by HS6288 series noise analyzer for noise operation point and spectrum analysis was performed to calculate the cumulative noise exposure (CNE). The pulse wave form analyzer was used to measure the noise exposure of 550 women in a textile factory (C 1, C 2, SBp, Dbp, Pp, and MAP) were observed in the observation group and 96 patients in the same group Female workers not exposed to occupational hazardous factors served as a control group. [Results] (1) Noise intensity of operating environment was 80.1 ~ 113.5dB (A), and the total point exceeded the standard rate was 92.5%. (2) In the observation group, 50 people were detected with hypertension, the detection rate was 9.1%; arterial compliance abnormalities were detected in 244 people, the detection rate was 44.4%, which was mainly C 2 reduction, accounting for the entire arterial compliance abnormalities Of 75.0%. (3) Sbp, Map and Pp in the observation group were significantly higher than those in the control group (P <0.05), while C_1 and C_2 in the observation group were significantly lower than those in the control group (P <0.05). (4) The Sbp, Map and Pp of noise exposure workers in workshop with noise exposure above 100dB were significantly higher than that of vehicle and control with noise <100dB (P <0.05) and C_2 significantly lower than that of control <0.05). (5) There was a negative correlation between Sbp, Dbp, Map and Pp in the observation group and C1 (P <0.01). There was a negative correlation between C_2 and age, Sbp, Dbp, Map and Pp in the observation group (P <0.01). (6) Multivariate regression analysis was conducted using C_1 and C_2 of the observation group as the dependent variables and age, cumulative exposure to the noise (CNE), Sbp, Dbp and Map as independent variables. From the equation it can be seen that Sbp is The main factors affecting C_1, C_2, followed by Dbp, CNE have a certain impact on C_1. [Conclusion] The compliance of large and small arteries of noise exposure workers in this mill was decreased, which indicated that prolonged exposure to noise could lead to impaired vascular function and decreased arterial elasticity.