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Brugada综合征是一种与室性快速心律失常敏感性增加有关的心脏结构正常的遗传性心脏病。临床表现为V_1~V_3,导联ST段抬高、右束支阻滞和猝死,这种心电图的间歇性发作已被报道,而临床上很难作出正确诊断。Brugada综合征患者心脏钠通道基因(SCN_5A)突变已被确定,因此,基因筛选检查有助于该病的诊断,尚不了解Brugada综合征的患病率,据估计如同长QT综合征那样
Brugada syndrome is a hereditary heart disease with normal cardiac structure associated with an increased susceptibility to ventricular tachyarrhythmia. Clinical manifestations of V_1 ~ V_3, lead ST segment elevation, right bundle branch block and sudden death, intermittent episodes of this ECG have been reported, and clinically difficult to make a correct diagnosis. The mutations in the cardiac sodium channel gene (SCN5A) in patients with Brugada syndrome have been identified and therefore genetic screening tests are useful in the diagnosis of the disease but are not yet aware of the prevalence of Brugada syndrome and it is estimated that as with the Long QT Syndrome