目的了解肠球菌引起医院感染的机率及耐药性变迁情况。方法对６年半来我院医院感染菌中肠球菌的比率及耐药性进行分析。结果肠球菌在医院感染菌中占的比例呈逐年上升的趋势，从１９９１年的４．４％上升到１９９７年上半年的１４．１％，尤其是泌尿系统以外部位的感染明显增多，对抗生素的耐药性也呈逐年上升趋势。结论该菌对多种抗生素呈高度耐药，易引起医院感染的流行，应引起临床的高度重视。 Objective To understand the incidence of nosocomial enterococci infection and drug resistance changes. Methods The ratio and drug resistance of enterococci in nosocomial infection in 6 years and a half in our hospital were analyzed. Results The proportion of enterococci in nosocomial infections was increasing year by year, from 4.4% in 1991 to 14.1% in the first half of 1997. In particular, the infection outside the urinary system was significantly increased. The drug resistance also showed an upward trend year by year. Conclusion The bacteria are highly resistant to a variety of antibiotics, easily lead to the prevalence of nosocomial infections, should cause clinical attention.