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目的:观察运脾消食汤合多潘立酮治疗脾虚食滞型功能性消化不良(FD)的临床疗效。方法:将符合诊断标准的160例FD患者按就诊顺序随机分为观察组与对照组,每组80例。两组患者均给予多潘立酮片,每次10 mg,3次/d。治疗组在此基础上加用运脾消食汤,水煎分服,1剂/d。两组均以7 d为1个疗程,治疗2个疗程后评价疗效。结果:痊愈率观察组为77.50%,对照组为52.50%,两组相比差异有统计学意义(P<0.05);总有效率观察组为97.50%,对照组为77.50%,两组相比差异有统计学意义(P<0.05)。恶心呕吐、食欲下降、上腹不适、嗳气、烧心、反酸等临床症状症状积分明显降低(P<0.05);治疗后较对照组改善明显(P<0.05)。结论:运脾消食汤合多潘立酮治疗脾虚食滞型功能性消化不良临床疗效显著,且可明显改善临床症状。
Objective: To observe the clinical efficacy of Yunpixiaozhi Decoction combined with domperidone in the treatment of functional dyspepsia (FD). Methods: According to the order of diagnosis, 160 cases of FD patients meeting the diagnostic criteria were randomly divided into observation group and control group, 80 cases in each group. Both groups were given domperidone tablets, each 10 mg, 3 times / d. On the basis of the treatment group, the patients in the treatment group received Yunpi Xiaoshi Decoction, decoction and decoction for one dose / d. Both groups were 7 days for a course of treatment, evaluation of 2 courses of treatment efficacy. Results: The cure rate was 77.50% in the observation group and 52.50% in the control group, with a significant difference between the two groups (P <0.05). The total effective rate was 97.50% in the observation group and 77.50% in the control group The difference was statistically significant (P <0.05). The scores of clinical symptoms such as nausea, vomiting, appetite decline, abdominal discomfort, belching, heartburn and acid reflux were significantly lower (P <0.05). Compared with the control group, the scores of symptoms improved significantly (P <0.05). Conclusion: The therapeutic effect of Yunpi Xiaoshi Decoction combined with domperidone on functional dyspepsia of the spleen deficiency type is significant, and can significantly improve the clinical symptoms.