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目的分析研究乳腺癌术中冰冻诊断准确性的病理影响因素。方法选取我院2014年7月到2015年6月收治的210例乳腺癌患者作为研究对象,回顾患者的基础病历信息以及诊断的病理资料,并分别对术中冰冻诊断肿瘤组织学大小、肿瘤分级等指标对其诊断准确率的影响进行分析。结果分别比较患者术中冰冻诊断、术后石蜡病理诊断的结果,可见肿物组织学大小的诊断准确率为84.7%,肿瘤分级的整体诊断准确率为78.1%,其中,肿物组织学大小>3cm患者的诊断准确率(93.8%)显著高于组织学大小≤3cm(80.8%)的患者,肿瘤分级为Ⅲ级(95.0%)的乳腺癌患者诊断准确率显著高于高于Ⅱ级患者(80.8%)高于Ⅰ级患者(71.2%)的情况,比较均有统计学差异(P<0.05)。结论乳腺癌患者的肿物的组织学大小、肿瘤分级等都会对其术中冰冻诊断准确性造成影响,把握这些病理因素的影响情况,是提高诊断准确性,促进手术顺利进行的重要依据。
Objective To analyze the pathological factors influencing the diagnostic accuracy of intraoperative frozen diagnosis of breast cancer. Methods Totally 210 breast cancer patients from July 2014 to June 2015 in our hospital were selected as research objects. The basic medical records and pathological data of patients were retrospectively reviewed. The histological size, tumor grade, And other indicators of the diagnostic accuracy of the impact of the analysis. Results The results of frozen diagnosis and postoperative paraffin pathology were compared respectively. The diagnostic accuracy of histological size was 84.7% and the overall diagnostic accuracy of tumor grade was 78.1%. Among them, histological size> The diagnostic accuracy of 3cm patients (93.8%) was significantly higher than that of patients with histological size ≤3cm (80.8%). The diagnostic accuracy of patients with tumor grade Ⅲ (95.0%) was significantly higher than that of patients with grade Ⅱ 80.8%) were higher than those in grade I patients (71.2%). There were significant differences between the two groups (P <0.05). Conclusion The histological size and tumor grade of tumor in breast cancer patients will affect the accuracy of intraoperative frozen diagnosis. To grasp the influence of these pathological factors is an important basis to improve the diagnostic accuracy and promote the smooth operation of the surgery.