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目的评价蚓激酶胶囊联合血塞通粉针治疗急性脑梗死的疗效和安全性。方法将120例急性脑梗死患者随机分为治疗组和对照组各60例,治疗组口服蚓激酶胶囊并静滴血塞通粉针,对照组静滴复方丹参粉针,均以14d为1疗程;观察两组患者治疗前后的凝血、纤溶、血液流变学指标,并评价患者的神经功能缺损程度和临床疗效。结果治疗组各项实验室指标均有明显改善,对照组则部分改善;神经功能缺损两组均有改善,但治疗组改善更为明显;两组患者均未出现明显不良反应。结论蚓激酶胶囊联合血塞通粉针治疗急性脑梗死有较好的疗效,且安全性好。
Objective To evaluate the efficacy and safety of lumbrokinase capsule combined with Xuesaitong powder injection in the treatment of acute cerebral infarction. Methods 120 patients with acute cerebral infarction were randomly divided into treatment group and control group of 60 cases, the treatment group oral administration of lumbrokinase capsule and intravenous infusion of plug, the control group intravenous infusion of compound Salvia powder, were 14d for a course of treatment The coagulation, fibrinolysis and hemorheology of the two groups were observed before and after treatment, and the degree of neurological deficit and clinical efficacy were evaluated. Results All the laboratory indexes of the treatment group were significantly improved, while those of the control group were partially improved. The neurological deficits were improved in both groups, but the improvement in the treatment group was more obvious. No obvious adverse reactions occurred in both groups. Conclusion Lumbukinase capsule combined with Xuesaitong injection can effectively treat acute cerebral infarction with good safety.