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介绍了超灵敏小型回旋加速器质谱计发展过程中出现的电场渗透、真空条件对束流传输效率稳定性和同位素比测量精度的影响、空间电荷效应和X射线本底等特殊现象和问题，以及通过多年的观察和实验，寻找到的克服和解决这些问题的办法。
The special phenomena and problems such as electric field infiltration, vacuum stability, efficiency of isotope ratio measurement, spatial charge effect and X-ray background appeared in the development of the ultrasensitive miniature cyclotron mass spectrometer were introduced. Years of observation and experimentation have found ways to overcome and solve these problems.