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目的:探讨健肾平喘汤联合硫酸沙丁胺醇气雾剂治疗哮喘患者的临床疗效。方法:将102例哮喘患者随机分为2组各51例,对照组给予硫酸沙丁胺醇气雾剂治疗,观察组给予健肾平喘汤联合硫酸沙丁胺醇气雾剂治疗,比较2组临床疗效、1秒钟用力呼气容积(FEV_1)以及不良反应。结果:总有效率观察组为92.16%,对照组为70.59%,2组比较,差异有非常显著性意义(P<0.01)。2组FEV_1值随着治疗疗程的延长而逐步升高,治疗后2、4、8周,治疗组FEV_1值均高于对照组.差异有显著性或非常显著性意义(P<0.05,P<0.01)。不良反应发生率观察组为1.96%,对照组为17.65%,2组比较,差异有非常显著性意义(P<0.01)结论:健肾平喘汤联合硫酸沙丁胺醇气雾剂治疗哮喘的疗效优于单纯硫酸沙丁胺醇气雾剂治疗,且不良反应少,值得临床推广。
Objective: To investigate the clinical effect of Jian Shen Ping Chuan Decoction combined with salbutamol sulfate aerosol in the treatment of asthma patients. Methods: A total of 102 patients with asthma were randomly divided into two groups (n = 51). The control group was given salbutaline sulphate aerosol. The observation group was given Jian Shen Ping Chuan Decoction combined with salbutamol sulfate aerosol. Forced expiratory volume (FEV_1) and adverse reactions. Results: The total effective rate was 92.16% in the observation group and 70.59% in the control group. There was significant difference between the two groups (P <0.01). The values of FEV_1 in two groups increased gradually with the prolongation of treatment course, and the values of FEV_1 in the treatment group were higher than those in the control group at 2, 4 and 8 weeks after treatment (P <0.05, P < 0.01). The incidence of adverse reactions was 1.96% in the observation group and 17.65% in the control group. There was significant difference between the two groups (P <0.01). Conclusion: Jian Shen Ping Chuan Decoction combined with salbutamol sulfate aerosol is better than asthma Simple salbutamol sulfate aerosol treatment, and fewer adverse reactions, it is worth clinical promotion.