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目的探讨小肠克罗恩病的临床特征及诊治经验。方法回顾性分析2006年1月~2013年1月复旦大学附属华山医院静安分院收治的小肠克罗恩病患者的一般资料、临床表现、辅助检查、治疗等相关临床资料。结果本研究共纳入60例小肠克罗恩病患者,男女比例2.53∶1,年轻患者多见,慢性起病;临床表现以腹痛腹泻为主,结肠镜及小肠钡灌肠是主要的检查手段;内科治疗后症状多能改善,外科治疗多针对穿孔、出血、梗阻等并发症。结论小肠克罗恩病临床表现多样,易漏诊误诊,应结合症状、影像资料及内镜检查结果进行综合判断。
Objective To investigate the clinical features and diagnosis and treatment of small bowel Crohn’s disease. Methods The clinical data, clinical manifestations, laboratory examinations and treatment of small bowel Crohn’s disease admitted to Jing’an Branch of Huashan Hospital affiliated to Fudan University from January 2006 to January 2013 were retrospectively analyzed. Results A total of 60 patients with small bowel Crohn’s disease were enrolled in this study. The ratio of male to female was 2.53:1. The young patients were more common and had chronic onset. The main clinical manifestations were abdominal pain and diarrhea, colonoscopy and small intestine barium enema were the main methods of examination. Symptoms can be improved after treatment, surgical treatment of perforation, bleeding, obstruction and other complications. Conclusions The clinical manifestations of small bowel Crohn ’s disease are diverse and easily misdiagnosed. Comprehensive judgments should be made according to the symptoms, imaging data and endoscopic findings.