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目的观察泮托拉唑钠注射剂对急性非静脉曲张性上消化道出血的疗效。方法在常规治疗的基础上治疗组40例,给与泮托拉唑注射液40mg+生理盐水100ml静脉滴注,12h1次,在1h内滴完,连用5d。对照组:甲氰咪胍0.6mg+5%葡萄糖溶液250ml,静脉滴注1次/d,连用5d。结果治疗组:显效34例(85%),有效4例(10%),无效2例(5%),总有效率95%;对照组:显效21例(52.5%),有效9例(22.5%),无效10例(25%),总有效率75%,2组总有效率有显著性差异(P<0.05)。结论泮托拉唑是治疗急性非静脉曲张性上消化道出血的有效药物。
Objective To observe the effect of pantoprazole sodium injection on acute non-variceal upper gastrointestinal bleeding. Methods Based on routine treatment, 40 patients in the treatment group were treated with intravenous infusion of pantoprazole 40mg + saline 100ml, 12h1 times, drip finished within 1h, once every 5 days. Control group: Cimetidine 0.6mg + 5% glucose solution 250ml, intravenous infusion 1 / d, once every 5d. Results In the treatment group, 34 cases (85%) were markedly effective, 4 cases (10%) were effective, 2 cases (5%) were ineffective and the total effective rate was 95%. The control group was markedly effective in 21 cases (52.5% %), Ineffective in 10 cases (25%) and total effective rate of 75%. The total effective rate in the two groups was significantly different (P <0.05). Conclusion Pantoprazole is an effective drug in the treatment of acute non-variceal upper gastrointestinal bleeding.