Objective: acute ischemic stroke is oc-curing in younger and younger individuals. This paper aims to explore the real-world epidemiological character-istics of young stroke patients in northwest Hubei. Meth-ods: the information of acute stroke patients under 50 years old in northwest Hubei Province was collected, in-cluding age, gender, region, education level, smoking and drinking, onset season, etc, and epidemiological analysis was carried out. Results: a total of 344 patients with acute ischemic stroke were surveyed. The males accounted for 69.19％, and the average age was 44.94 ± 5.61 years old; the females accounted for 30.18％, and the average age was 45.22 ± 5.02 years old. The distribution of patients varied, with most living in urban areas. There were more male patients than female patients. The proportion of pa-tients with an education level below junior high school was higher than that of patients with an education level above junior high. Twenty-nine point thirty-six percent of all young people with stroke smoked and drank. Stroke occurred in all seasons, but the incidence of stroke was relatively high in summer and autumn. There was a sig-nificant difference in the ratio of males to females (P < 0.001). Conclusion: the incidence rate of acute stroke in young people in northwest Hubei Province is unique. With the increase of age, men in all ages are more prone to strokes than women. The incidence of stroke among young people in urban areas is higher than in surrounding counties. The incidence rate decreases with the increase of education level. More strokes occur in summer and au-tumn than in winter and spring. Smoking and drinking do not show obvious effects on the incidence rate.