洗必泰(Hibitane)化学名为1,6-双-(N-对氯苯双胍)己烷,简称双氯苯双胍己烷,为一种常用的消毒防腐药,医疗上多用于器械、皮肤、粘膜消毒。近年来国外还用于口腔消炎,抑制牙斑形成,治疗痤疮和手术过程中的腹腔、肠道粘膜消毒等。洗必泰对革兰氏阳性及阴性菌具有抑菌、杀菌作用,药力比新洁尔灭等强,即使有血清、血液等存在仍然有效,对许多真菌及酵母菌、毛滴虫及生长期带孢子菌种的生长也有抑制作用,因此,是一种较理想的广谱抑菌、杀菌剂。洗必泰为白色无臭具有苦味的结晶粉末,稍溶于水及乙醇。可与盐酸、醋酸、菊萄糖酸、碘结合成盐,以葡萄糖酸洗必泰的水溶解度最大(1:5),其次为醋酸洗必泰(1:55)、盐酸洗必泰(1:1700)和洗必泰碘(1:2,000)。目前国内临床常用的为醋酸洗必泰, Hibitane chemical name is 1,6-bis- (N-p-chlorophenyl biguanide) hexane, referred to as chlorhexidine, is a commonly used disinfectant antiseptic medicine, used for medical equipment, the skin , Mucosal disinfection. In recent years, foreign countries also used for oral anti-inflammatory, inhibit plaque formation, the treatment of acne and surgery in the abdominal cavity, intestinal mucosal disinfection. Chlorhexidine has antibacterial and bactericidal activity against Gram-positive and -negative bacteria, and its potency is stronger than that of benzalkonium bromide. Even though serum, blood and the like are still effective, chlorhexidine has a positive effect on many fungi and yeasts, trichomoniasis, The kind of growth also has inhibitory effect, therefore, is a more ideal broad-spectrum antibacterial, fungicide. Chlorhexidine white odorless crystalline powder, slightly soluble in water and ethanol. It can be combined with hydrochloric acid, acetic acid, glutamic acid and iodine to form salt. Chlorhexidine gluconate has the highest water solubility (1: 5), followed by chlorhexidine acetate (1:55), chlorhexidine hydrochloride (1 : 1700) and chlorhexidine iodine (1: 2,000). At present, the domestic clinical commonly used for chlorhexidine acetate,