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目的 探讨应用生物半透膜密闭包扎治疗指端组织缺损的临床应用效果.方法 2012年8月至2013年12月,对20例20指指端组织缺损病例均采用生物半透膜密闭包扎治疗,创面大小为1.0cm×l.0cm~2.5cm×2.0cm,其中创面有骨质外露12例.所有创面均清创后采用生物半透膜直接密闭包扎,每5~7d更换半透膜时只需用生理盐水冲洗创面,无需殃伏消毒.结果 本组病例均获得6~ 18个月的随访,20例指端创面均无感染发生,愈合时间为3~6周.新生皮肤质地接近正常,两点分辨觉为7~ 10 mm,功能、外观满意.结论 应用生物半透膜密闭包扎治疗指端组织缺损效果满意,是一种较为理想的治疗方法.“,”Objective To discuss the clinical application and effect of treating tissue defect on the finger tip with airtight semipermeable dressing technique.Methods From August 2012 to December 2013,20 cases (20 fingers)of tissue defect on finger tip were treated with airtight semipermeable dressing technique.There were 12 cases with bone-exposure.The defect size was from 1.0 cm × 1.0 cm to 2.5 cm × 2.0 cm.All cases were treated with biological membrane directly to cover the defects.The wound was cleaned with saline and replaced with a new semipermeable membrane every 5 to 7 days.Results The wound and donor site in 20 cases all healed without infections.The 20 cases were follow-up for 6 to 18 months.The texture and color of the new skin were similar to those of adjacent normal skin,with a satisfactory appearance without obvious contracture.The two-point discrimination was 7 to 10 mm.Conclusion Airtight semipermeable dressing technique could be an ideal method of treating soft tissue defects on fingertip.