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目的 :检测人参皂苷Rg2 是否有致突变作用。方法 :在动物急性毒性试验的基础上 ,采用体内微核技术、哺乳类细胞染色体畸变和Ames实验。结果 :从真核细胞及原核细胞水平检测人参皂苷Rg2 无致突变作用。结论 :人参皂苷Rg2 低毒、无致突变作用。
Objective : To test whether ginsenoside Rg2 has mutagenic effect. Methods : On the basis of animal acute toxicity test, micronucleus technique in vivo, chromosome aberration of mammalian cells and Ames experiment were used. Results : Ginsenoside Rg2 was not detected to be mutagenic from eukaryotic and prokaryotic levels. Conclusion: Ginsenoside Rg2 is low-toxic and non-mutagenic.