将制剂厂生产的三个批号的样品分别熔封于安瓿中,每批分成三组,各组分别以60℃、70℃:80℃、作恒温加速破坏试验。使用萃取分光光度法测定颠茄酊中莨菪碱的含量,它是以甲基橙作显色剂,不受水解产物的干扰。以时间(天)作横座标,log为纵座标,证明颠茄酊水解反应符合一级反应动 Three batches of samples produced by the preparation plant were respectively melted in ampoules, and each batch was divided into three groups. Each group was subjected to accelerated destructive test at a constant temperature of 60 ° C and 70 ° C: 80 ° C. The extraction spectrophotometry was used to determine the content of scopolamine in the belladonna tincture, which is based on methyl orange as a color reagent, without interference from hydrolyzate. The time (days) for the horizontal axis, log for the vertical axis, indicating that belladonna tincture hydrolysis reaction in line with a reaction