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乙型肝炎病毒(HBV)致肝细胞损伤机理十分复杂。一般认为,HBV 不直接杀伤肝细胞,而是通过在肝细胞内表达抗原或与细胞基因整合,诱导免疫损伤或促成细胞恶性变。本文将着重简述近几年有关对 HBV感染与肝细胞损伤关系的研究进展。
Hepatitis B virus (HBV) induced liver cell injury mechanism is very complicated. It is generally believed that HBV does not directly kill liver cells but induces immune damage or contributes to malignant transformation by expressing or integrating with genes in hepatocytes. This article will focus on the recent research progress on the relationship between HBV infection and hepatocellular injury.