植化在新药评价中的主要任务与作用

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新药不外乎来源于:中草药、天然产物和人工合成品.所谓中草药,是指我国中医传统使用的中药,流传于民间的草药和民族药(应包括国外的植物药和民间药等);天然产物是指来源于自然界的产品,包括植物、动物、矿物等等.抗菌素也是天然产物,早已形成独立的领域.植化就其研究范围和内容是十分丰富的,这里是针对研究中草药和天然产物的化学而言.因为植物药历来占居多数,故习惯上称为植化.从中草药和天然产物寻找新药的结果,或是提供新型药物应用于临床;或是开创药物新类型,为人工合成新药指明方向;或是一药多用和老药新用.就筛选新药而言,从中草药和天然产物比从人工化学合成品的筛药阳性率高.一般认为,中草药的毒性比较低,付作用小,也没有耐药性.五十年代以 The new drugs are nothing more than those originated from: Chinese herbal medicines, natural products and artificial synthetic products. The so-called Chinese herbal medicines refer to traditional Chinese medicines used in traditional Chinese medicine, herbs and national medicines that are popular in the private sector (should include foreign plant and folk medicines, etc.); Products are products derived from nature, including plants, animals, minerals, etc. Antibiotics are also natural products that have long formed an independent area. Phytochemistry is very rich in the scope and content of its research. Here is a study of Chinese herbal medicines and natural products. In terms of chemistry, because plant drugs have historically occupied the majority, it is customarily called phytochemicals. The results of seeking new drugs from Chinese herbs and natural products, or providing new drugs for clinical use; or creating new types of drugs for artificial synthesis The direction of the new drug indicates; or one drug is used more often and the old drug is newly used. For the screening of new drugs, the positive rate of screening drugs from Chinese herbs and natural products is higher than that of synthetic chemicals. It is generally believed that the toxicity of Chinese herbs is relatively low, and the effect is low. Small, no resistance. In the fifties
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