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目的比较放化疗与单纯放疗治疗小细胞肺癌的疗效差异。方法 2007年1月-2008年6月收治小细胞肺癌患者48例。在患者知情同意的前提下,随机分为放化疗结合组27例和单纯化疗组21例。观察并比较两组的治疗效果。结果放化疗结合组和单纯化疗组总有效率分别为88.9%(24/27)和66.7%(14/21),放化疗结合组高于单纯化疗组(P<0.05)。放化疗结合组和单纯化疗组1年生存率分别为74.1%(20/27)和57.4%(12/21),放化疗结合组高于单纯化疗组(P<0.05)。结论放化疗综合治疗小细胞肺癌可改善患者临床症状和生活质量,延长生存期。
Objective To compare the curative effects of radiotherapy and chemotherapy with radiotherapy alone in the treatment of small cell lung cancer. Methods From January 2007 to June 2008, 48 patients with small cell lung cancer were admitted. In the informed consent of patients under the premise, were randomly divided into radiotherapy and chemotherapy combined group of 27 patients and chemotherapy alone in 21 cases. Observed and compared the treatment effect of two groups. Results The total effective rate was 88.9% (24/27) and 66.7% (14/21) in radiotherapy and chemotherapy combination group and chemotherapy alone group, respectively. The radiotherapy and chemotherapy combination group was higher than the chemotherapy alone group (P <0.05). The 1-year survival rates of radiotherapy and chemotherapy combination group and chemotherapy group were 74.1% (20/27) and 57.4% (12/21), respectively. The radiotherapy and chemotherapy combination group was higher than the chemotherapy alone group (P <0.05). Conclusion Chemotherapy combined with chemotherapy for small cell lung cancer can improve clinical symptoms and quality of life of patients and prolong survival.