目的　观察深层巩膜切除联合羊膜植入对开角型青光眼的近期治疗效果。方法　对 15例 18眼原发性开角型青光眼患者行深层巩膜切除联合羊膜植入手术 ,术后观察视力、眼压、前房反应和滤过泡情况。结果　术前平均眼压为2 7.7mm Hg± 8.3m m Hg(1k Pa=7.5 m m Hg) ,术后 3个月平均眼压为 15 .1mm Hg± 4 .6 mm Hg ,差异有显著性 (P <0 .0 1) ,平均眼压下降幅度为 4 5 .5 % (12 .6 mm Hg)。单纯手术治疗术后眼压控制≤ 2 1mm Hg者 11眼 (6 1.1% ) ,需加用局部降眼压药物方可控制眼压者 6例 (33.3% )。术后发生浅前房、前房积血各 1例 ,未观察到脉络膜脱离、黄斑水肿、白内障及眼内炎等严重并发症的发生 ,所有病例术前与术后1、7d、3个月视力统计学差异无显著性。结论　深层巩膜切除联合羊膜植入能有效降低开角型青光眼患者眼压 ,且并发症少 ,视力恢复快 ,是一种很有临床应用前景的抗青光眼术式。 Objective To observe the short-term therapeutic effect of deep sclerectomy combined with amniotic membrane implantation on open-angle glaucoma. Methods Fifteen patients with primary open angle glaucoma underwent deep sclerectomy combined with amniotic membrane implantation. Visual acuity, intraocular pressure, anterior chamber reaction and filtration bleb were observed after operation. Results The average preoperative intraocular pressure was 2 7.7 mm Hg ± 8.3 mm Hg (1k Pa = 7.5 mm Hg). The mean intraocular pressure at 3 months after operation was 15.1 mm Hg ± 4.6 mm Hg, with significant difference (P <0. 01), the average IOP decreased by 45.5% (12.6 mm Hg). Simple surgical treatment of postoperative IOP ≤ 2 1mm Hg in 11 eyes (6.11%), the need to add local intraocular pressure medication to control intraocular pressure in 6 cases (33.3%). One case had shallow anterior chamber and posterior chamber hemorrhage, and no serious complications such as choroidal detachment, macular edema, cataract and endophthalmitis were observed. All patients were treated with preoperative and postoperative 1,7 and 3 months Visual acuity difference was not significant. Conclusion Deep sclerectomy combined with amniotic membrane implantation can effectively reduce the intraocular pressure in patients with open angle glaucoma, and less complications, rapid visual acuity, is a very promising clinical anti-glaucoma surgery.