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以水蛭（ＨｉｒｕｄｅｎｉｐｐｏｎｉｃａＷｈｉｔｍａｎ）、蚂蟥（ＷｈｉｔｍａｎｉａｐｉｇｒａＷｈｉｔｍａｎ）、柳叶蚂蟥（Ｗ．ａｃｒａｎｕｌａｔａＷｈｉｔｍａｎ）３种动物即水蛭类药材的干燥体为材料，进行了抗凝血作用的实验研究．结果表明，３种动物的干燥虫体，都有抗凝血物质存在，都具类似尿激酶样抗栓酶的生物活性．
The anticoagulant effect was studied by using dry bodies of three kinds of animals, namely Hirudenipponica Whitman, Whitmaniapigra Whitman and W.acranulata Whitman. The results showed that dry insects of all three species had anticoagulant substances and all had similar biological activity to urokinase-like antithrombotic enzymes.