目的探讨重型颅脑损伤开颅术后大面积脑梗死的诊断与治疗。方法总结本科2001年5月~2006年5月收治的12例重型颅脑损伤开颅术后大面积脑梗死的临床特点、CT或MRI诊断和治疗。结果重型颅脑损伤开颅术后大面积脑梗死导致病情加重,出院时12例疗效评定中良好4例,中残3例,重残2例,植物生存1例,死亡2例。结论重型颅脑损伤开颅术后病情发生变化时应及时复查CT或MRI,使其并发的大面积脑梗死及早得到诊断与治疗。 Objective To investigate the diagnosis and treatment of large area cerebral infarction after craniotomy in severe craniocerebral injury. Methods The clinical features, CT or MRI diagnosis and treatment of 12 cases of severe craniocerebral injury after craniotomy were summarized in our department from May 2001 to May 2006. Results Large cerebral infarction after craniotomy in severe craniocerebral injury led to aggravating conditions. Out of 12 patients, 4 were well evaluated, 12 were moderate disability, 2 were severe disability, 1 were plant survival and 2 were fatal. Conclusion Severe craniocerebral injury after craniotomy should be timely review of CT or MRI changes, so that complicated by large areas of cerebral infarction and early diagnosis and treatment.