目的:吗啡在治疗急性心源性肺水肿上的临床疗效和预后观察。方法:对我院急诊抢救室收治的109例急性心源性肺水肿的患者,在诊断明确后,给予吸氧及基础药物的常规治疗上,分成吗啡组(55例)和对照组(54例)。对照组患者给予常规治疗,吗啡组在对照组的基础上加用吗啡静脉注射,观察记录在治疗1h后患者的相关生理参数的改变、插管率以及1周后病死率,并对此进行统计分析。结果:相较于对照组,吗啡组能更快使患者肺水肿得到改善,临床症状更快得到缓解(P<0.05),短期疗效更优,但插管率增加,病死率无明显改善(P>0.05)。结论:吗啡联合常规治疗治疗急性心源性肺水肿短期疗效更好,但插管率增加,病死率无明显改善。 Objective: Morphine in the treatment of acute cardiogenic pulmonary edema clinical efficacy and prognosis. Methods: A total of 109 patients with acute cardiogenic pulmonary edema admitted to emergency room of our hospital were divided into 2 groups: morphine group (55 cases) and control group (54 cases) ). The patients in the control group were given routine treatment. The morphine group was intravenously injected morphine on the basis of the control group, and the changes of relevant physiological parameters, intubation rate and mortality after 1 week were recorded and statistically analyzed analysis. Results: Compared with the control group, the morphine group could improve the pulmonary edema and relieve the clinical symptoms faster (P <0.05), and the short-term curative effect was better, but the intubation rate was increased and the mortality rate was not significantly improved (P > 0.05). CONCLUSION: The short-term curative effect of morphine combined with conventional therapy in the treatment of acute cardiogenic pulmonary edema is better, but the intubation rate increases and the case fatality rate has no significant improvement.