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细胞周期素D1(Cyclin-D1)是与甲状旁腺肿瘤发生有关的重要分子之一。Cyclin-D1基因表达与调控在甲状旁腺肿瘤的发生中起重要作用。Cyclin-D1的表达与调控有转录水平与转录后水平两种,其影响甲状旁腺肿瘤发生的具体机制一直是研究的热点。Cyclin-D1基因的研究对甲状旁腺肿瘤的诊断治疗和提示预后有重要意义
Cyclin D1 is one of the important molecules involved in the parathyroid tumorigenesis. Cyclin-D1 gene expression and regulation plays an important role in the occurrence of parathyroid tumor. Cyclin-D1 expression and regulation of transcription and post-transcriptional levels of two, the specific mechanism of affecting the parathyroid tumor has been a hot spot. The study of Cyclin-D1 gene is of great significance for diagnosis and prognosis of parathyroid tumor