利用2,4二硝基氟苯和绵羊红细胞分别制备小鼠细胞和体液免疫反应模型,在测定小鼠耳肿胀度和抗体生成量的同时,用放免法分别测定细胞和体液免疫反应小鼠脾中cAMP、cGMP含量及其比值,同时观察炎喜康的作用。结果表明,炎喜康10mg/kg,ig×5d能使细胞免疫反应小鼠脾中cGMP含量增加,使cAMP含量下降;而该药10mg/kg,ig×5d则使体液免疫反应小鼠脾中cGMP含量下降,cAMP与cGMP比值略高于对照组。 A mouse cell and humoral immune response model was prepared using 2,4 dinitrofluorobenzene and sheep erythrocytes, and mouse ear swelling and antibody production were measured. Meanwhile, cellular and humoral immune responses were measured using a radioimmunoassay mouse spleen. In the cAMP, cGMP content and its ratio, while observing the role of Yan Xi Kang. The results showed that Yanxikang 10mg/kg, ig×5d could increase the content of cGMP in the spleen of mice with cellular immune response and reduce the content of cAMP; while the drug 10mg/kg, ig×5d caused the humoral immune response in the spleen of mice. The cGMP content decreased, cAMP and cGMP ratios were slightly higher than the control group.