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目的探讨代谢综合征(MS)组分与结直肠腺瘤性息肉(CAP)的关系,探讨MS组分对预测CAP的价值。方法分析2007年1月至2010年12月行电子结肠镜检查的242例住院患者的临床资料,根据是否患有CAP分为CAP组(137例)和对照组(105例),调查各组患者身高、体重、血压、血脂及血糖情况,应用多元logistic回归分析CAP与各指标的关系。结果 CAP组BMI、WC、SBP、TG水平均明显高于对照组,HDL-C水平明显低于对照组,差异均有统计学意义(P<0.05,P<0.01)。CAP组MS、高血压、血糖异常和血脂异常发生率(分别为40.9%、59.9%、31.4%、43.1%)均明显高于对照组(分别为9.5%、37.1%、11.4%、24.8%),差异均有统计学意义(P<0.05)。腹型肥胖、高血压和高甘油三酯血症是CAP发病的危险因素(P<0.05)。结论 MS患者是CAP发病的高危人群,应作为CAP的重点筛查对象。
Objective To investigate the relationship between metabolic syndrome (MS) and colorectal adenomatous polyps (CAP) and to explore the value of MS for predicting CAP. Methods The clinical data of 242 hospitalized patients undergoing electronic colonoscopy from January 2007 to December 2010 were analyzed retrospectively. All patients were divided into CAP group (137 cases) and control group (105 cases) according to whether they had CAP or not Height, weight, blood pressure, blood lipids and blood glucose, multivariate logistic regression analysis of the relationship between CAP and various indicators. Results The levels of BMI, WC, SBP and TG in CAP group were significantly higher than those in control group, and the levels of HDL-C in CAP group were significantly lower than those in control group (P <0.05, P <0.01). The incidence of MS, hypertension, dyslipidemia and dyslipidemia in CAP group were significantly higher than those in control group (40.9%, 59.9%, 31.4%, 43.1% respectively) (9.5%, 37.1%, 11.4%, 24.8% , The differences were statistically significant (P <0.05). Abdominal obesity, hypertension and hypertriglyceridemia were risk factors for CAP (P <0.05). Conclusion The MS patients are the high risk group of CAP and should be the key screening target of CAP.