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目的了解北京市城区就诊的急性散发腹泻病例中病原感染分布现状,为制定相关防治策略提供依据。方法以北京市宣武医院就诊的腹泻病例作为监测对象,留取粪便标本进行霍乱弧菌、副溶血弧菌、志贺菌、沙门菌和致泻性大肠杆菌等多种肠道致病菌和轮状病毒、诺如病毒的检测及分析。结果 2011-2013年共调查并检测腹泻病例429例,总阳性率45.5%,细菌培养阳性率19.3%,病毒检测检出率为30.8%,有20例患者便检结果细菌、病毒皆为阳性。结论北京市城区就诊的急性散发腹泻病例病原型别复杂多样,且有鲜明的季节流行特征,每年应在流行高峰来到之前,通过实施各类综合防控措施以减少感染性腹泻疫情的发生。同时应进行必要的腹泻病原学监测及研究,以进一步明确本辖区感染性腹泻的流行特征。
Objective To understand the distribution of pathogen infection in acute disseminated diarrhea cases in Beijing urban area and provide evidence for the establishment of relevant prevention and treatment strategies. Methods The cases of diarrhea treated by Xuanwu Hospital in Beijing were taken as the monitoring objects. Stool samples were collected for pathogenic bacteria such as Vibrio cholerae, Vibrio parahaemolyticus, Shigella, Salmonella and diarrheal Escherichia coli Like virus, Norovirus detection and analysis. Results A total of 429 cases of diarrhea were investigated and detected in 2011-2013, with a total positive rate of 45.5%. The positive rate of bacterial culture was 19.3%. The detection rate of virus was 30.8%. In 20 cases, the results of bacteria and virus were all positive. Conclusions The pathogenic forms of acute diarrhea cases in Beijing urban area are complex and diverse, and have distinctive seasonal epidemic characteristics. Each year, various epidemic prevention and control measures should be taken to reduce the occurrence of infectious diarrhea before the epidemic peak arrives. At the same time, the necessary diarrhea etiology monitoring and research should be carried out to further clarify the epidemic characteristics of infectious diarrhea in this area.