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牙囊细胞是一类具有异质性的细胞群,可分化形成牙周组织。调控牙囊细胞分化的机制十分复杂,上皮—间充质之间的相互作用扮演着重要的角色,其导致牙囊细胞分化相关基因的程序化表达过程又被一个包括多种细胞因子在内的分子调节网络控制。下面就牙囊细胞及其分化调节机制作一综述。
Dental cells are a group of heterogeneous cell populations that differentiate into periodontal tissues. The mechanisms that regulate the differentiation of dental follicle cells are complex and the interaction between epithelial-mesenchymal cells plays an important role. The programmed expression of genes involved in the differentiation of dental follicle cells has been further investigated by a multi-cytokine Molecular Regulation Network Control. Here is a summary of the mechanism of the dental follicle cells and their differentiation.